Hello! I hope you are still having fun. Given that there is a bit of luck involved in determining the perks and blueprints you receive, your high score can fluctuate, especially when you haven't unlocked the upgrades. Is your score improving with each run?
If it feels overwhelming at first, try placing the building in the space where it yields the highest score. Over time, you will notice and learn different building synergies and patterns.
Additionally, if you have any ideas for improvements, please share them!