We have seen it works, and probably needs some steps to follow to start it, like unziping it and setting file as executable, then it works fine.
Viewing post in World of Sisters & (Early Access Updates) comments
These are the instructions from someone who play it on MacOS:
(It's from older version guide but it should work - I personally do not own MacOS and never used it so I can maximally google with you)
MacOS:
Guide made by our fan - you can't just copy paste, check the file location / rename to match
1) Unzip file
2) move .app file to Application directory
3) Open Terminal app, write this: sudo chmod -R +x Applications/World\ of\ Sisters.app/Contents/MacOS/ and write user password
4) System Preferences -> Security& Privacy -> World of Sisters -> Open Anyway
sudo chmod -R +x /Applications/World\ of\ Sisters\ 0_19_1\ \(MacOS\).app/Contents/MacOS/