The problem is :
1. I do not used Itch Launcher, I just play the game directly from your download links
2. You misunderstood about point 1, what I mean is : if you Click and HOLD CTRL at same time, it caused conflict between skip and clicking, thus clicking will be disabled as long as I hold the left CTRL before clicking to anything on the screen. This was not an issue at older patches, but 0.36 and newer have this issue whenever I did that (Holding CTRL while tried to click on the screen)