I don't have exact numbers to give, but for me invokeai3 takes more than ten seconds before each invoke starts processing, even with just one LORA. In ComfyUI it seems to be instant with 10 LORAs. My CPU is weak, so that might be part of the reason, but there might be some optimisations to be done, because I don't have any problems with ComfyUI. Maybe the problem is that invokeai doesn't keep LORA's in memory and therefore loads them every time, whereas ComfyUI does. I have no idea and I'm not an expert, just a guess.