The patch notes have some hints on what to do. But, you absolutely need the grenade Arthur -throw it earlier in the battle to save some people. If you have the armor and super weapons, it'll make the fight easier. If you went to the pirate ship, make sure you steal back your weapons and put them in the armory (I believe this is a room on floor 2). But, being at a higher level with better weapons and lots of energy grenades will help.