My underwear vanishes from my inventory every time I load the game. I buy more, it doesn't show in my closet. I use cheats and put some on, click to leave the closet, the outfit saves but the underwear comes off. Is this a glitch or am I missing something?
It sounds like you picked up the "Commando" perk, either by taking Exhibitionist, or choosing not to wear underwear for several days in a row. As far as I know, there's no way currently to remove this perk without editing game files.
Based on player feedback, the dev mentioned he might revisit how this perk functions in the future.