24582 damage with 6 Aracks, android and recycler. I just one shot three final bosses! This game is awesome. Took me six hours of playtime for the cards to fall right, though. Please don't nerf them!
The second best turn was 2000+ with full board of hellhounds and over 5000 with hellhounds and box jellyfish.\\\
Edit: Got golden goo run finally. Got over 4K damage with claymore mine, with each golden goo doing 80 damage. In the end they were doing 111 damage each. How to replicate (hah!): Self replicating spider, grey goo, mystery box and hope you are lucky and get gold goo.