I got it to run on my MacBook Pro 15" 2016 and even though performance wasn't the best it was playable. Thanks to the developer for also including a Mac version in the first place :)
To run it, the commands listed above didn't work for me. The first two commands are okay. After the second command is already in the right folder, leaving out the "TheProfessional.app/Contents/MacOS/" part worked for me (so only "chmod +x The\ Professional") and then instead of opening it via "Control + Right Click" it should be opened with "Option + Right Click".