I was getting a report of this:
While running game code:
ScriptError: Name (u'game/satisfactionUpgradesAndItems/init_satisfactionUpgrades.rpy', 1623503967, 2) is defined twice, at game/satisfactionUpgradesAndItems/init_satisfactionUpgrades.rpy:73 and game/schedules/satisfactionUpgradesAndItems/init_satisfactionUpgrades.rpy:73.
I deleted both and hit reinstall in Itch.io, seemed to fix it for me.
Edit: yeah, getting a lot of errors in game, not sure if it is a save issue or file issue, unplayable atm, don't have time to investigate further atm.