Bug found: Its about the Booster potion. Each time I log in the game the recipe its available to study it. I tried saving the game. I logged out and in again and I had to study it once more.
Does this bug still happen even you have learn this recipe and go to another place and save it? Sometime ren'py couldn't save a process during brewing screen, maybe ren'py cannot detect a change in this screen, except you exist that screen and save it later.