Excellent puzzle game! I had a similar issue on PC (screenshot is identical whenever a level loads the first time, but no crash), and it looks like it’s because the game is reverting the tiles to the default Puzzlescript non-overlapping 5x5px ones. Since you have a couple mods installed for extra height and overlap in your sprites, I’d check that code. It might be the sprite_size from PuzzleScriptPlus interfering with the variable sprite heights from PuzzleScript#.
I may take a look at this myself at some point, because the mods you used are pretty great. Will let you know if that leads anywhere, as I can consistently replicate this bug.