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There are enough community roles that you could play 10 with no repeats, and folks can always invent their own factions too—it's more just a matter of how long you want to play! Like, with a standard deck of 52 cards, 10 players could take 5 turns each without having to fetch a new deck, but 50 turns could take a long time depending on how detailed people want to be in their descriptions. 

It's plenty fun with low player counts, but I most often play in the 3-6 range! That way you can get a full rotation in, clock how long it takes, and then play as many full rounds as you have time/energy for without worrying about running out of cards or any one round being TOO long. Especially since the math works best if everyone plays an equal number of turns.

Hope this helps!