I've read through Wanderhome multiple times and have listened to a couple Actual Play podcasts, though I haven't had the opportunity yet to run a game with my own game group.
First of all, the book is a beautiful thing even if you just flip through for the art. The saturated, whimsical style of the art is just nice to look at. Then there's the descriptions of the natures for kith and for places that are great for getting your mind working imagining a character or a place or a story all on their own.
If just the book can bring me back this much, I can't wait to get a Guide-less game going with my usual group.