I'm not able to get past 30 Lust or initiate BJ scene with the brother, don't know if I'm doing anything wrong.
But yeah, as it was stated, the fatigue goes from 100 to 0 without any warnings, which has resulted in some annoying sudden deaths. But so far I've manage to deal with that using auto saves. Though even then I've gotten stuck in some nasty deathloops, which i have managed to wiggle out luckly.
Personally i enjoy the update so far, even with the bugs. The brother is adorable, good job!