Yes I would like to echo the many comments about how well polished this game was! I didn't try all the combos but I did try each item. I really like that the variability was more than a simple stat change and you put effort into projectiles, secondary ability differentiation, etc. Not sure if I saw all the enemies - my high score was 14,700 and things were pretty intense!
I cannot really offer suggestions here, it is just so well put together! Maybe a sound to indicate that my ability had recharged would have been handy? And the sprites looked a bit rough with the antialiasing on my 2K resolution. Nitpicking, really, because the entry was great.
Congratulations on the good work! This will be a frontrunner, I think.