This is a great concept, and I think you're on the right track with the execution as well. From what I was able to figure out, poking at the game objects in Tabletop Simulator, I saw a lot of cool stuff. The surprise cards especially are a nice touch. Plus, hey, alchemy! It's a good theme for a (virtual) board game.
I'm not sure I completely figured out the mechanics - that's probably mostly on me, though, since I'm not at all familiar with Tabletop Simulator. You could make the game more accessible to people who have the dumb like me if you include a more comprehensive manual. Maybe a video tutorial with a sample game? I feel like that would've helped me.
I'd love to see a more standalone version of this game, because there's definitely potential here.