I love all the graphics and animations, and the mouse too, it all makes for a very beautiful game. Some text isn't in the pixel art font which felt kind of out of place though. If you haven't already, consider making a font file which allows you to make edits to common place text and last minute changes a lot more easily.
I think the flashing on the items were a bit too much for me, it felt like a strobe light. Maybe make the flashing slower, or just not flash at all.
In my first playthrough, I was pretty confused what was going on since almost nothing was really explained in the game itself, but I quickly realized what was going on once I woke up and reset for a 2nd run (since I didn't try to remember any of the items in the rooms). A skip cutscene button would be nice for multiple playthroughs.
Maybe include that there's only 1 alien per room since its only really said in the description of the game, and not in the game itself.
This little guy over here subverted my eyes because it was behind the UI ;-; (images aren't working for some reason, but its just a prop completely covered by the UI in the top left)
Most of these are just little nitpicks to possibly improve the quality of life in the game and make it feel better, but I have no major complaints. I'm not very good at prop hunt games and my memory is kind of garbage so I could barely pass minimal (I think that's just me being bad lol), but it was a fun little game.
:>