Tried this game with a couple of friends, tasked with rescuing a kidnapped princess from a castle in the Ransom Duchy, and while it took them a little while to shift gears out of D&D and get into Mayhem Mode, they were definitely starting to get it by the time one squire coaxed his Archery 1 knight into shooting blindly into a melee, then botched the emergency surgery on the other knight. Everyone had a ton of fun, and it was really helpful that the worldbuilding is exactly wacky enough that I could make the twist at the end "the lady of the castle is actually the princess's girlfriend and the kidnapping is basically an elaborate form of roleplay" and have it not feel out of place.