On phone no, it will be deleted, but others i dont know, didnt checked on computer, if have a save file in game folder and u delete the folder, well yes, but if its like documnets no
Windows backs up EVERY Ren'Py game variable file (persistent, saves, etc) in the C:\Users\*your login name*\AppData\Roaming\RenPy directory. This is why when deleting a RenPy old version before installing a new version, the saves still exist. They're there...