Hello, the AMD GPU sometimes have a hard time running the cloth simulation. You can go in the setting again and set cloth physics to "none" instead of low. This usually solves the issue but you can't see any cloth anymore.
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The option to deactivate clothes is not present in the demo because it is supposed to be censored. However, you can open the file QualitySettings.txt and set the cloth parameter to 3.
This issue is still on the top of our todo list and we are working on it but we haven't been able to reproduce it on our side so far, so it's not simple. We hope to push a fix for the next version or the one after.