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There are many ways to increase your clinic's fame in fact:

- Each time you perform an examination you earn 5 points for a perfect exam, 3 for an above average exam, 1 for a normal exam. You will also get -3 points for a bad exam and -5 for a very bad one.

- At the gym when you meet Daniel (random chance) he will challenge you with questions about fashion. Based on the difficulty of the question you can get 1 to 5 points answering correctly

Clinic's fame influences how much you get from "automatic exams" (when you don't have a scripted exam or you refuse to play a random exam (coming to Patrons this month with male/female children).
You can also trade fame to increase your patient's trust level in medical exams. If you think a patient's trust level is too low you can use your clinic's fame to increase it. Each trust level costs 15 fame points, so you can only do that if your fame is enough.