I'm having this issue too. Do you know what the Company Name and Product Names are for this game?
what you want to do is type regedit into the search bar and open it
then you go to HKEY_CURRENT_USER\Sofware\noid.pizza\Yo! Noid2: Enter the Void
from there, you can just highlight all the controls and delete them, and the next time you open the game they will be back to default.