Does this work smoothly on i7-10750H ,GTX 1650, 8gb Ram
yes this is work normali just try to optimise your pc whis Razer Cortex or anothers software to end processes you do not have to run whis gaming ;)
yes on medium graphics (shift+2)
I have almost the same setup as you except I have a GTX 1660Ti and 16GB of RAM and I can easily set it to max and it is still well playable
