An isometric game is interesting! I don't see those often in jams. Though, I do wonder if the game would be better if the movement wasn't isometric. It makes the controls feel stiff for what is seemingly meant to be an action game.
It seems the main strategy is to keep running while shooting at the enemies as they chase you, which did lose my interest quickly. Maybe the later waves would be more interesting, but I would get caught on a rock or tree and lose my health almost immediately when an enemy touched me, so some invincibility frames would have helped me.
Overall, nice job! I really like the pixel art and music. Were the assets made for this game?