You also have to make sure to have Natalie send you a photo that morning and not have Milly send it. When you do both things she has a VERY different reaction to the drug.
Assuming you don't mind spoilers, with the dom path instead of making Milly passive it makes her aggressive. They go back to Andrea's house and she screws her a couple times. Milly tells Andrea at the end that she owns her now (paraphrasing). I definitely prefer this one over the sub, which was still good but made me a little uncomfortable with how it went down.