Nice concept.
Not sure where you want to take this game but form things that annoys me.
- Game won't work in background (easily fixed with few changes in project setting)
- Day cycle is simply to long, waiting from 9-18 is 9 minutes... probably should be cut to half of it, or like 4 minutes for 8 hours in game time.
- Already mentioned by someone, but when girls take pills they just leaving rather than stay for a moment for her transformation to end.
For future.
Think about making every part of a character model adjustable, it will save you headache later on, even if this will take more time to implement right now. So lets say you will have a single character model where you will only change breast size, muscle size, head/hair etc. rather than making own model for each character.
I kinda regret not going with such approach in my game.
Think about adding cheaper supplements (they can do nothing for now), so player has easier time making money.