It's a pretty alright experience. After the first couple of days I spent a lot of time moving stuff around so they're all easier to access when I need to fix or resupply stuff. lmao
It helps that you're typically worried about just 1-2 tasks at a time after the frantic first few minutes, so it's never completely overwhelming once you get past that.
The only big issue I had is when the mouse stops working when you click or tab out, so it was mildly annoying to have to restart twice when I just wanted to write down my thoughts. But it seems to be a problem that's shared with a lot of web builds, so it's not exactly the game's fault.