[insert transfem seal of approval on the yuri]
The game concept is quite cool and unique! I also liked the art and overall visuals. There are some issues with the balancing, but you can only do so much for a roguelike in 4 days :3. One thing you should think about is more time with the shopkeep upping the contrast on the UI in the shop and having icons for each powerup which you can hover over for more information. Rule of thumb - if it's meant to be viewed quickly it should also be understood quickly. And also having some indicator on the health of each mob (like a health bar that pops up over the mobs when they get hit, and goes away after it hasn't been hit in a while to reduce screen clutter). Fun game!