Honestly kinda rad having the game balanced around completing it without any mutations. Getting the extreme endings (best / bad) was all about compromising to make your play style work. Really cool concept and execution.
I did run into a few bugs here and there though, particularly with combining some mutations and some shield mutations sometimes turning the shield on? I also don't particularly think it makes sense to unlock shield mutations before you're supposed to have one.
Very fun entry though, good job.