I can launch it manually, but not within the application.
i'm not sure what the problem might be, if you're talking about the itch.io app then it might be some problem with it because i have never checked if that worked with the game, but it might be a problem with the installation?
if you're on windows there is a known problem when rendering for some people that can be solved by
- launch the game -> shift + g -> change rendeerer -> close and open again