Incredible concept you have here! The mechanics are very polished and intuitive, and very enjoyable. You really have to adapt the way you play depending on the enemies you are facing, giving it much more depth.
I would have preferred if everything could be done with the gamepad (navigating the menu, ...), but it is always nice to see games supporting them. Also, I think the info and tips screen before a level stays displayed a bit too shortly, maybe it would be better with user input.
I don't have a lot of time right now and I kinda suck at it, but you can feel that this is the kind of game where you can progress and get the hang of it very quickly. Nice job!