ENTIRE GAME SPOILERS BELOW.
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Your wife dies for emotion points. Doesn't matter of what, or what you do.
Ask her to get snacks rather than come straight home from the grocery? She fucking dies of covid, despite being young and explicitly having no other health problems.
Fail to get her vitamins, masks, an extended prescription, wipes, and five other things? Suggest them in the wrong order so that she cuts you off before you get to everything? Whoops, she dies of covid again.
Get past that? Miss a doctor's appointment and she dies of a fucking brain tumor.
Get past that? Apparently Light Yagami has her number, because at the end she dies of heart failure no matter what you do. No way to prevent it. This is the best ending you can get.
There are five endings: in three of them your wife dies as described above. In the other two you reject her and she can be safely presumed to die without you knowing, because she's as sickly as a Victorian maiden.
It's not sad, it's just silly. It lessens the emotional impact, enough so that I don't even remember the characters' names at this point.
You can make choices as a player, yes! But you have no real agency to carve out your fate. Despite the art and dialogue being of excellent quality, that makes the whole game sour.
This review isn't kind, so I'm sorry. I liked Angela's other stuff. I love most lesbian VNs, and it's plain to see the amount of effort put into it. But I still really don't like this one, because you weren't able to do anything. Links are to TVTropes, beware.