It’s accompanied by a system message.
Software Failure, Axion_060, Program failed (error #80000003), Wait for disk activity to finish. Suspend/Reboot
If I hit suspend, and I start the game again, I will make it to the main menu, but if I hit U to update, the game crashes and the error code it throws is #80000028 and then forces a reboot (which is then met with a guru mediation, error 8000 000B tasl 08A2D760).
I am running in the lowest resolution.