Had a ton of fun with this one. It's incredibly clever and well laid out. After a quick read, I probably could have run it straight out of the book, though I did do some prep to make it smoother.
It took my group (me and 3 players, all new to Mothership) a very leisurely 2 and a half sessions to finish, about 8–9 hours total (they saved the ship). I ran it as advised, starting a day before the incident and using the full timeline.
It's an excellent module, especially for introducing people to the system. I intentionally went a bit easy on my players (they were already sweating), but for larger/more experienced groups I recommend shortening the timeline and making the rest of the ship's crew an active problem if not handled well, potentially violent.