All downloads are 1000% safe. Ryanshow has been around for quite a while now. If he wanted to just plant bugs on people's computers. They had multiple opportunities to do so by now. From 'less credible' places to boot, like Aryion.
I get wanting to be cautious. But to be honest. It's not as if downloading straight from ANY site. Is exactly safer than downloading it from some other external place.
(I'm not a computer nerd, so I don't have exact faith in what I say next.) If anything, having an external download lessens the risk of malware. I feel as if it's much easier for someone to plant a bug. If they themselves have less hoops to jump through. Such as of course, straight downloads from Itch.io.