INCREDIBLE GAME!
For such a popular genre, this game is very unique and one of my favorites I've seen.
First off, when is this coming to steam? I'd wishlist it asap.
Then, some issues:
When drawing a card from the pack, I got multiple copies of it (or drew the same card multiple times), either way it should be more clear that you get multiple copies of a card or prevent drawing the same card.
As others have mentioned, you can bust the first turn without any input :/
Finally, curses are really annoying - when getting them it changes a 1/6th of your deck to a curse, so you cannot have multiple types, otherwise you'll bust every time. This is just a suggestion, but you could make it so you offer two cards to be "sacrificed" or something and they get a random curse, to make it easier to control what's in your deck.
Overall, love the game, love the art style (although the map is very cluttered) and can't wait keep playing this!