I didn't saw any of the new modifications so I can't really say much for now, but I want to write this because I think my save file is corrupted in some way?
So, it doesn't matter in what moment of the game I am, my cards start showing like this

Having this black side and losing half the strength. And when I finish the fight, my card is replace by 3 or so 1 atk/1 def "blue" cards that act like red cards and have no mod space, like this one:

So, at the start I thought it was one specific enemy that did something like this, but when I started a new run it happened agian, even on the first area. I'm pretty confused how this could happen, to be honest. There's other modificators, like the cannot grab card that some enemies put, that last forever instead of only for the fight. I don't know if that's intentional but as far as I remember the first versions didn't had that?
Plus, when you have 0 mana and the free knife effect, you can't use the knife anyways, and when you equip things to a card when you show deck after a fight (in the reward scene, where u choose the mods and etc) the card is not affected and what you added is deleted. The first problem I guess I will just try to continue playing in a new save but yeah idk how that could happen, so better if I tell you that it is possible :P