I'll third what SergeantArcade said. Definitely an increased curser click size would be a big step in the right direction. I've seen a few idle clicker games use a small radius that can be increased. It could be a whole new upgrade stat. Personally; I'd really like to see audio be prioritized for the next update you do. Without any sound it's hard to immerse yourself. Idle clickers are a game where you can really lose track of time because you're so focused on the game that you just don't realize how long it's been. Without sound, I did not get immersed that way. I do think that as the game progresses the manual clicking is going to end up completely irrelevant no matter what you do, but you might be able to extend its usefulness by making the automated upgrades require a little more work before you can be rewarded with them. Or possibly making the bonus multiplier add to the passive income (it might already but by the time I bought my first couple I was already constantly losing crumbs)
One thing I noticed was that I'd lose my bonus multiplier without a chance to save it when the spawner was at an edge of the screen. It might shoot the crumb off the screen almost immediately, so I'd have no time to save it. Perhaps it could have a boundary a little bit away from the screen edge to make it a bit more forgiving
I'd also like to let you know that I had several moments where the upgrades I tried to purchase took two clicks to activate. Not entirely sure what's happening there.