It's a jam game, so the balancing being completely borked is expected. But it's pretty egregious. Also it isn't really clear that it's nearly impossible to get rid of organs. It's *very* unintuitive to skip rewards with open inventory slots, to save them for better organs later. But you still have to pick anything with one of the 4 or so actual useful stats. Or you won't make the very tight stat checks from the bosses. But if you do, once you're in zone 3. Your organs have simply been outscaled by the enemies, as they are insanely tanky while also having tonnes of damage. To the point where an average zone 3 enemy is arguably stronger than the zone 2 boss. I don't see any feasible way, outside of insane luck, to get past that point.
Oh and if you have time sensitive inputs that the player needs to make during combat, it's not an auto battler, and it shouldn't be tagged as such.