I've been doing all-boot into all-cube collections. (Edit: Misworded that before but basically the strategy phaluzak outlined, of using boot artifacts to get squares then switching all forge artifact slots to cubes to max return on blue squares) So far I'm up to about e55 blue and e16 pink. I have maxed out the prestige shop. I am one row away from getting to the next screen. I'm excited to have green squares. (Once every couple orders of magnitude I sacrifice too, boost bonus time is now like +10k seconds)
Since the cube artifacts don't multiply the pinks, it can be worth it to farm a few collections with all-boots active in the forge.
Also I haven't seen anyone say this but obviously while the boots are in place, before switching to cubes, I reroll to get as many 9s and as few 3s as possible
Edit: updated numbers. Things have been slowing down around e55