I've yet to try this but I think the winning item combo might be shrinking ray on Sam Temp on Red and Nano (mini robot) on Vix. defeat the slime queen twice drain the mage or healer but make sure you drain something as Red first action and give it to the robot. spam mend after the queen gone (cannot be revived or fully drained) The mad scientist is easy so should fine with the mini robot you can bypass the thorn effect that hitting the taunt gold of the dragon thanks to the Marking that the mini robot can do shrinking the malice and marking the malice should take them out even though they are stun immune they are not seduce immune which does lower their damage shrinking Miss D should reduce her damage and marking her should would make all your attack crit on her Not sure if she's Stun immune since when I fought her I was using Grow and shrink and clock. And I brought her down to yellow health I blame the Dragon gold since I did take alot of self damage hitting that gold.