If the MC itself isn't really directly involved in any lewd content, the game could go the route where the player isn't referred to by any gender pronouns and whatever gender the player wants to be can just be headcanon'd, as it's not relevant in gameplay.
Basically you'd have free reign to pick any selection of boobs, beards, long hair, short hair, maybe body shape ears and tails(?) and that's it.
Dunno if you've got plans for romance or sex or whatever that might throw a wrench in having an unspecified protagonist though.