Since this game uses the "female appearance with male genitals" style of futanari (instead of the "full-package" kind with both male and female genitals), I wouldn't expect the scenes and game mechanics to really change all that much.
Not that there's really all that many male characters to swap anyway. The only ones to get any real screentime are the player character and 2 companions, and you can make first of them match the game's futa characters already by just slecting breasts and a feminine body-type.