Great questions.
It should work without any issues on AMD.
On the Giants version, currently no. However, I believe I can make it work with other distributions.
Can you tell me the path to your install?
Thanks!
I installed it to my second drive "D:\Farming Simulator 2025"
I did try running it, it loaded steam, gave me an error (which I suspected it would), then launched the game like I normally do.
Here is a screenshot