Is there a way to breed Doctor Quinn twice? Also if I'm a male there's no way to kiss your partners. Also would like the option of making all futa characters female. and lastly I'd like the option to breed Socket
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4: Finish sockets quest line and you can do that.
2: To do the lotus sex position which can be achieved by your partner having a penis or wearing a strap-on.
3: You can change the generic NPCs spawn settings in the ME menu ingame. If you want to change all the futas that are generic NPCs use tf pills or just forget them and they're gone. All static NPCs can not be changed unless where available.
1: As for Eliza you have a lot of chances even more when you do the lab assistant quest line and can just ask her to have sex.
Edit: added the numbers
4: yes... Her womb isn't broken or in need of repairs though. She will ask you a question about that in her quest line.
2: that's why I gave you the option of strap-on to. You can equip a strap-on on to a female character or anyone without access to a dick during sex if you have one in your inventory available.