"Its always this one tune. Its so simple, yet so memorable, and the fact that I always bleed out or suffocate or faint forever very soon after hearing it makes it make me feel all the more hopeless about my situation" This reminds me a lot of the learned helplessness phenomenon lmao.
I wanna add too that Biological Exclusion Zone and the distorted version of There's Landmines On The Desert must be my favourites song of the game, for the second one, i only understand it plays when the character has a lot of debuffs; i heard it during my last run in the newest update, all i can say is that it didn't fail on making things feel more desperate and hopeless.
As for Biological Exclusion Zone, the song itself gives me the feeling melancholy and slight hopelessness; i only remember hearing it once in the wasteland layer and i was dealing with infections, a fracture, low mood, opioid craving and surely many other debuffs. All this combined made the current situation feel more miserable, i still tried to save the character until i finally realised there was no way out, so as last resort i tried killing him with mushrooms and overdose to make the death less painful; yet somehow the experiment still survived, i'm not sure if it was by a last stand or some kind of cursed miracle, but in the end, the character was left paralyzed and with a brain integrity of 27%, so i could only wait for starvation to finally end the run. Moments like these is the main reason why i love so much this game.