Download and install both the emulator and the renpy plugin. Then extract the zip file in a folder. Then add the game and run it. Make sure to download the latest version of joyplay cause the older ones seem to kinda crash for no BS.
Well, I have the latest version of both Joiplay and Renpy, but it still doesn't run. I don't know if there's another version, but according to the emulator's page, I have the latest version