The hands are pretty OP, I wish they attacked a bit more slowly or something.
The room mechanic is very cool, but it accentuates a problem that the game has: since the enemies are reasonably tough and there aren't many chokepoints you're encouraged to run past them. If the dice have limited to six shots for an entire set of rooms it just further encourages that playstyle. These games can be notoriously hard to gate and nail the level design of, and this is a mistake I've made many times. Even in my latest entry I had to aggressively playtest it out of the game (to yet to be judged degrees of success).
There's an idea here, and the core top-down gameplay is solid.