If I had a nickel for every time a hentai game used my families genetic disease as a plot point, I'd have 2 nickels. Still it's odd, slightly annoying, and immersion breaking for me. Not fun to be reminded of my personal Sword of Damocles when I'm in escapist fiction.
Not really your fault. Short of making up an entirely new disorder, someone is going to be touched no matter which disorder you choose.