It's not like they have a real choice; they can either stay with the gamers and lose all possible income (and inevitably go bankrupt), or be forced to play by the rules.
However, placing the entire blame on itch.io is not right either; if someone is to blame, it's the payment companies and conservative groups.
As for what we are supposed to do, not much other than to complain about it.
Like over here: https://chng.it/vbgCC4Nsf8